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Research Martin Styner
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WHY ARE VOLUME MEASUREMENTS NOT ENOUGH? WHAT DO WE GAIN IF WE DESCRIBE
SHAPE?
AN EXAMPLE, Lateral Ventricles of Twins
| Original brain images displayed on this page
are provided by following source:
Original brain images for Ventricles
mono/dizygotic twin study, Daniel Weinberger, NIMH Neuroscience
at St. Elizabeth, Washington
Ventricle segmentation
MHNCRC Imaging Lab at University
of North Carolina
A transparent head with lateral ventricles (smoothed data)
is visualized to the right (click to enlarge image).
Animations: Ventricle + Hippocampus,
Ventricle
+ sliced brain
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8 samples from the Weinberger mono/dizygotic Twin study were selected
(4 Twins). Their lateral ventricles were segmented. The volumes of the
ventricles were measured and normalized to the intracranial volume. Since
theories in neuromorphological research point out that Twins should have
similarly structured brain morphology, we should be able to
detect the
Twin pairs by studying their ventricles (within certain limits, conditions).
Find the Twin pairs ......
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relative volume ratio of left to right lateral ventricle |
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absolute (normalized) volume of right lateral ventricle |
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Each dot represents the volume measurement of one of the 8 samples.
Try to find the Twin pairs by grouping the 8 dots to pairs, either in the
absolute volume plot or in the volume ratio plot.
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Top view of Shape - Find the Twins...
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Try to find the twins by grouping the 8 shapes into pairs
using above top view images.
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Compare your solution to the ground truth
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relative volume ratio of left to right lateral ventricle, numbers
indicate the corresponding pairs |
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absolute (normalized) volume of right lateral ventricle, numbers
indicate the corresponding pairs |
Shape solution (not as surprising as for the volumes...)
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Twin Pair 1
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Twin Pair 2
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Twin Pair 3
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Twin Pair 4
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The Twin pair numbers correspond to the numbers in the solution
of the volume plots.
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How many Twin pairs did you match successfully using the volume measurement
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How many Twin pairs did you match successfully using the shape visualization
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Very possibly you were able to identify most of the Twin pairs using
the shape visualization and few of them using the volume measurement...
Martin Styner
